Most patients with a parathyroid tumor will have low Vitamin D-25 levels. Those patients with more severe primary hyperparathyroidism (those with larger tumors and those who have had the tumor a longer time) will have higher blood calcium levels, which are associated with lower Vitamin D-25 levels.
Hyperparathyroidism is a disease entity that occurs due to increased secretion of parathyroid hormone (PTH) from parathyroid glands and causes hypercalcemia. 1 Secondary hyperparathyroidism is a response to low calcium levels related to hypovitaminosis D.
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High blood calcium, low normal pth, very low vitamin d, negative sestamibi scan. My pth is low normal at 22. My vitamin D is very low, at 19. I’m very fatigued, muscle and joint pain, especially hips, sleep poorly, have aweful brain fog and memory issues. My sestamibi scan was negative for any parathyroid adenomas, or anything abnormal with my parathyroids.
Low vitamin D, high parathyroid hormone levels linked in hyperparathyroidism. In addition, patients with vitamin D deficiency were younger (mean age, 57 years vs. 59 and 67 years, respectively; P = .001) and weighed more (mean weight, 181 lb vs. 174 lb and 157 lb; P = .053). Researchers found no between-group differences in HR-pQCT,
Low PTH levels may be caused by: Damage to the parathyroid gland, which can by caused by neck surgery or radiation treatments. A rare disease, such as sarcoidosis or histiocytosis X. An overdose of vitamin D or calcium. Cancer, such as lymphoma or multiple myeloma. A low magnesium level.
I am like you (except my PTH is a bit higher at 5) but sometimes my Ca does dip so even though the test was normal, I tried to explain to the doc that I am drinking gallons of milk etc. to try to keep my levels up and sometimes when I am away from home I cannot keep up my diet and my levels lower. My D is chronically low as well. Are you seeing an endo? Like you, I am not able to get treated with synthetic PTH but I basically use a high calcium diet to help me and lots of vitamin D3.Hi thanks for replying, been to the endocrinologist but he sad I am normal and there is nothing to worry about as my calcium level was always normal also that I couldn’t be truly vit d defficient as my pth would be high. I am not really sure what all this means I did feel like they thought I was wasting their time : ( do your calcium results always come back ok.Vitamin D is also a very important hormone, not just for calcium levels. I would be concerned that your levels are so low. You can buy vitamin D3 over the counter in health food stores. It is not expensive, and is the best way to supplement vitamin D. You could try a dose of say 5000 IUI daily for a month and then retest to see if your levels had come up, and then adjust dose from there. From what i’ve read D levels should be at least mid-range and preferably on the higher end of the range.Hi I have tried vitamin d2 from the pharmacy and then vitamin d3 prescribed by the doctor and both times my kidneys were really sore and I felt quite unwell, so now I am a bit dubious. I don’t understand why my vitamin d is so low when it’s been summer and I have been outside a lot what will my levels be in summer : ) thanks for commenting everyone : )Silly me, i meant what will my levels be in winter : )Low PTH levels may be caused by: Damage to the parathyroid gland, which can by caused by neck surgery or radiation treatments. A rare disease, such as sarcoidosis or histiocytosis X. An overdose of vitamin D or calcium. Cancer, such as lymphoma or multiple myeloma. A low magnesium level. I had a severe magnesium deficiency which caused my low PTH, vitamin D deficiency and calcium deficiency. Calcium can be normal in the early stages of magnesium deficiency but as the deficiency state worsens this eventually leads to calcium deficiency. To note: ionized calcium is more accurate than serum calcium. Magnesium is the most important co factor for vitamin D absorption. If you live above the 35 degree latitiude (eg: 2/3 of the US/ Canada, Europe) there is no UVB rays (that create vitamin D) from November through to March due to the angle of the sun.Thanks for commenting, I am in Lancashire so there is not much hope of getting any vitamin d. I’ve had my magnesium levels checked and they were ok. I am just going to see how I get on this winter. I don’t know about the rest of you but I go through phases were I feel ok and then I go down hill and feel really tired. I am a chemist so I am considering testing my ionized calcium levels my self, can’t face going back to the doctors. Hope your all well : )My calcium is always borderline low, sometimes low. But *They* say it is ok. Huh. I only had ionized run once it was normal – again on low side. Urine calcium readings are high. I take a lot of D and a lot of calcium (mostly in the form of food). I think D is under-rated – they should pay more attention to it! It is a hormone too!
High PTH levels could be caused by overactive parathyroid glands. This is called hyperparathyroidism. However, there are other potential causes of high PTH levels, such as: Inherited low vitamin D