Hirschsprung’s disease affects about one in every 5,000 newborns. Children with other congenital conditions, such as Down syndrome and heart defects, are more likely to have the disease. Parents who carry the code for Hirschsprung’s disease in their genes, especially mothers, may pass it …
Hirschsprung Disease. Hirschsprung disease (aganglionic megacolon) occurs when some of the nerve cells that are normally present in the wall of the intestine do not form properly during fetal development. All children with Hirschsprung disease require surgical treatment.
About Hirschsprung Disease. Hirschsprung (HERSH-sproong) disease affects the large intestine (colon) of newborns, babies, and toddlers. The condition — which prevents bowel movements (stool) to pass through the intestines due to missing nerve cells in the lower part of the colon — is caused by a …
Hirschsprung disease occurs in approximately one in 5,000 newborns. Children with Down syndrome and other medical problems, such as congenital heart defects, are at much greater risk. For example, about one in 100 children with Down syndrome also has Hirschsprung disease. Hirschsprung disease is congenital,
Hirschsprung disease. In Hirschsprung disease, the nerves are missing from a part of the bowel. Areas without these nerves cannot push material through. This causes a blockage. Intestinal contents build up behind the blockage. The bowel and abdomen swell as a result. Hirschsprung disease causes about 25% of all newborn intestinal blockages.
Hirschsprung’s disease is the congenital absences of ganglion cells in the rectum and the lack of these cells causes an obstruction of the large bowel. These babies may present at birth a delay to pass meconium (a dark green poop in newborns) for more 24 hours or have abnormal bowel movements associated with abdominal distention and vomiting.
Hirschsprung’s disease is a condition that causes a baby to be born with nerve cells in his or her intestines missing. Sometimes the missing nerve cells affect only a small part of the bowel. In other cases, large sections of the nerve cells are missing. Hirschsprung’s disease causes 15 to 20% of intestinal obstructions that occur in newborns.
Examination of infants affected with Hirschsprung disease reveals: Abdominal distention. Infants with aganglionic megacolon show tympanitic abdominal distention and symptoms of intestinal obstruction. Chronic constipation. Older infants and children with Hirschsprung disease usually present with chronic constipation. Palpable intestinal loops.
History. However, the disease is named after Harald Hirschsprung, the Danish physician who first described two infants who died of this disorder in 1888. Hirschsprung’s disease is a congenital disorder of the colon in which certain nerve cells, known as ganglion cells, are absent, causing chronic constipation.
Hirschsprung disease occurs in approximately 1 in 5,000 newborns. Children with Down syndrome and other medical problems, such as congenital heart defects, are at much greater risk.For example, about one in 100 children with Down syndrome also has Hirschsprung disease.